Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty

Active, not recruitingOBSERVATIONAL
Enrollment

53

Participants

Timeline

Start Date

April 30, 2016

Primary Completion Date

February 29, 2020

Study Completion Date

December 31, 2025

Conditions
Sepsis
Interventions
OTHER

Frailty Measurements

"A frailty index will be determined as a combination of factors.~An older adult is considered physically vulnerable when they experience:~1. muscle weakness~2. fatigue~3. low physical activity, and unintentional loss in body weight, which has been agreed upon by a consensus of experts.~This will be collected at baseline, 3, 6 and 12 months."

OTHER

Modified Minnesota Leisure Time Activities

A questionnaire used to assess physical activity will be administered at baseline, 3, 6 and 12 months.

OTHER

Computed tomography morphometrics

A CT scan will occur as standard of care while the patient is hospitalized. Two additional CT scans will occur at 3 and 12 months to assess for sarcopenia.

OTHER

Mobility Monitors

Mobility monitors will be placed on the patients during the duration of their hospital stay. They will then where them at 3, 6 and 12 months for up to 10 days.

Trial Locations (1)

32610

UF Health at Shands hospital, Gainesville

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

collaborator

National Institutes of Health (NIH)

NIH

lead

University of Florida

OTHER

NCT02711709 - Persistent Inflammation, Immunosuppression and Catabolism Syndrome (PICS): A New Horizon for Surgical Critical Care and Induced Frailty | Biotech Hunter | Biotech Hunter