NCT02710331View on ClinicalTrials.gov

Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Substudy III

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
CannabisAlcohol EffectDriving Under the Influence of Alcohol and Other Drugs
Interventions
DRUG

Active Dronabinol

10 mg capsule of Dronabinol will be administered orally.

DRUG

Placebo

Control: no alcohol, administered for \~80 minutes.

DRUG

Placebo

Control: Placebo pill (no active cannabinoids) administered orally.

DRUG

Active Ethanol

Target BrAC of 0.04% reached over 20 minutes and then clamped to maintain this dose for an additional 60 minutes. This dose is equivalent to consuming approximately 2 drinks over 1 hour. Administered over a total of 80 minutes.

Trial Locations (1)

06516

Biological Studies Unit, VA Connecticut Healthcare System, West Haven

All Listed Sponsors
lead

Yale University

OTHER