35
Participants
Start Date
February 29, 2016
Primary Completion Date
April 11, 2017
Study Completion Date
April 11, 2017
Glycerinated German Cockroach Allergenic Extract
"Participants will receive escalating doses intranasally. Briefly: per protocol- Phase 1a NAC: N=10 cockroach sensitive adults with asthma will undergo nasal allergen challenge with dose escalation (up to 8 doses per protocol). Phase 1b: Phase 1a subjects will have repeat NAC with dose escalation (up to 8 doses).~Phase 2: N=25 cockroach sensitive children with asthma (ages 8 - 14 years) will undergo NAC with doses determined by Phase 1a data (e.g., symptoms and safety data)."
Children's National Medical Center, Washington D.C.
Cincinnati Children's Hospital, Cincinnati
UT Southwestern Medical Center, Dallas
Children's Hospital Colorado, Aurora
Inner-City Asthma Consortium
NETWORK
National Institute of Allergy and Infectious Diseases (NIAID)
NIH