the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation

PHASE3CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

April 30, 2016

Primary Completion Date

December 31, 2020

Study Completion Date

April 30, 2021

Conditions
Gastrointestinal Vascular Malformation
Interventions
DRUG

Thalidomide (100mg)

Patients were randomly assigned to receive a 120-days course of 100 mg of thalidomide (Pharmaceutical Co., Ltd. of ChangZhou, China).

DRUG

Thalidomide (50mg)

Patients were randomly assigned to receive a 120-days course of 50 mg of thalidomide (Pharmaceutical Co., Ltd. of ChangZhou, China).

DRUG

placebo

Patients were randomly assigned to receive a 120-days course of placebo (Pharmaceutical Co., Ltd. of ChangZhou, China).

Trial Locations (10)

100032

Peking Union Medical College Hospital, Beijing

200025

Ruijin Hospital, Shanghai

200032

Shanghai Zhongshan Hospital, Shanghai

200040

Huashan Hospital, Shanghai

200092

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

200127

Department of Gastroenterology, Renji Hospital, Shanghai Institute of Digestive Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai

200433

Changhai Hospital, Shanghai

201620

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

400037

Xinqiao Hospital of Chongqing, Chongqing

510515

Nanfang Hospital of Southern Medical University, Guangzhou

All Listed Sponsors
collaborator

Peking Union Medical College Hospital

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Xinqiao Hospital of Chongqing

OTHER

collaborator

Changhai Hospital

OTHER

collaborator

Shanghai Zhongshan Hospital

OTHER

collaborator

Huashan Hospital

OTHER

collaborator

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

collaborator

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

collaborator

Ruijin Hospital

OTHER

lead

Shanghai Jiao Tong University School of Medicine

OTHER

NCT02707484 - the Efficiency of Thalidomide for Recurrent Small Intestinal Bleeding Due to Gastrointestinal Vascular Malformation | Biotech Hunter | Biotech Hunter