NCT02696993View on ClinicalTrials.gov

Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer

PHASE1/PHASE2Active, not recruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 16, 2016

Primary Completion Date

December 31, 2027

Study Completion Date

December 31, 2027

Conditions

Metastatic Malignant Neoplasm in the BrainStage IV Non-Small Cell Lung Cancer AJCC v7

Interventions

PROCEDURE

Cognitive Assessment

Ancillary studies

BIOLOGICAL

Ipilimumab

Given IV

OTHER

Laboratory Biomarker Analysis

Correlative studies

BIOLOGICAL

Nivolumab

Given IV

RADIATION

Stereotactic Radiosurgery

Undergo SRS

RADIATION

Whole-Brain Radiotherapy

Undergo WBRT

Trial Locations (1)

77030

M D Anderson Cancer Center, Houston

All Listed Sponsors

lead

M.D. Anderson Cancer Center

OTHER

NCT02696993 - Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer | Biotech Hunter | Biotech Hunter