Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

February 23, 2016

Primary Completion Date

February 15, 2017

Study Completion Date

February 15, 2017

Conditions
Methicillin-resistant Staphylococcal Infections
Interventions
OTHER

Early vancomycin monitoring and bayesian dosage adjustment

Measure of vancomycin serum concentration at the 3rd hour of treatment and adjustment of vancomycin dosage at the 6th hour of treatment using a bayesian approach. Then measure of vancomycin serum concentration at the 24th hour of treatment.

OTHER

usual vancomycin dose and monitoring strategy

Vancomycin serum concentration will be measured at the 24th hour of treatment.

Trial Locations (1)

75015

Hôpital Necker-Enfants Malades, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER

NCT02694458 - Comparison of Two Dosage Adjustment Strategies of Vancomycin in Children | Biotech Hunter | Biotech Hunter