Neoadjuvant J591 Treatment for Prostate Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

February 4, 2016

Primary Completion Date

February 10, 2017

Study Completion Date

February 2, 2020

Conditions
Prostate Cancer
Interventions
DRUG

huJ591

Antibody is derived from a hybridoma originally produced in the Weill Medical College Laboratory of Urological Oncology. Treatment with 100 mg of HuJ591 will be administered as an intravenous infusion at a concentration of 5 mg/mL and rate of \<5 mg/minute.

DRUG

89Zr-J591

Drug product is manufactured by the radiochemistry staff of Citigroup Biomedical Imaging Center (CBIC) research core facility. Radiolabeling of DFO-huJ591 with 89Zr is achieved by the addition of 89Zr-oxalate to the DFO-huJ591 in ammonium acetate buffer.

Trial Locations (1)

10065

Weill Cornell Medical College, New York

All Listed Sponsors
lead

Weill Medical College of Cornell University

OTHER

NCT02693860 - Neoadjuvant J591 Treatment for Prostate Cancer | Biotech Hunter | Biotech Hunter