80
Participants
Start Date
February 29, 2016
Primary Completion Date
May 31, 2016
Study Completion Date
May 31, 2016
Spinal anesthesia
Performed at the L3-4 or L4-5 interspace using 27- or 25-gauge spinal needle.
Intrathecal bupivacaine
Bupivacaine 12.5 mg will be administered in the subarachnoid space.
Intrathecal fentanyl
Fentanyl 15 µg will be administered in the subarachnoid space.
Cesarean delivery
Lower segment cesarean section using the Pfannenstiel incision and exteriorization of the uterus.
Wound infiltration
30 mL bupivacaine 0.25% will be injected subcutaneously in the surgical wound (15 mL on the upper and lower sides) by the obstetrician before skin suturing.
Sham procedure
Sham procedure will be performed after surgery by moving the ultrasound probe and pressing a covered spinal needle on both sides of the patients' abdomen.
Transversus abdominis plane block
Bilateral ultrasound-guided TAP block using 20 mL bupivacaine 0.25% on each side. A 7-12 MHz linear array probe and 22-gauge needle will be used. The probe will be placed transversely above the iliac crest in the anterior axillary line and the needle will be introduced in-plane with the probe from medial to lateral.
Ketorolac
IV ketorolac 30 mg/8 h starting at the end of surgery.
Paracetamol
Oral paracetamol 1 gm/8 h starting 4 h after surgery.
Fentanyl patient-controlled analgesia
Intravenous fentanyl: bolus dose = 20 µg, lockout interval = 7 min, 4-h dose limit = 200 µg, with no background infusion.
Department of Anesthesia, Mansoura University Hospitals, Al Mansurah
Mansoura University
OTHER