Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

286

Participants

Timeline

Start Date

December 15, 2015

Primary Completion Date

September 26, 2019

Study Completion Date

April 23, 2020

Conditions
Geographic AtrophyDry Age-Related Macular Degeneration
Interventions
DRUG

Avacincaptad Pegol

Avacincaptad Pegol 20 mg/mL solution for intravitreal (IVT) injection

OTHER

Sham

The Sham procedure included the blunt opening of an empty, needleless syringe barrel placed on the conjunctiva in the inferotemporal quadrant of the eyeball to simulate the pressure of an injection.

Trial Locations (78)

1076

Peterfy Korhaz-Rendelointezet Orszagos Traumatologiai Intezet, Budapest

1083

Budapest

1106

Budapest

1133

Budapest

1145

Budapest

4012

Debrecen

6720

Szeged

7621

Pécs

8200

Veszprém

10138

East Tallinn Central Hospital, Tallinn

11412

Dr.Kai Noor Eye Clinic, Tallinn

13224

Syracuse

14620

Rochester

15000

Axon Clinical SRO, Prague

15122

West Mifflin

19107

Philadelphia

20815

Chevy Chase

21209

Baltimore

23235

Richmond

28210

Charlotte

28602

Hickory

28803

Asheville

29169

West Columbia

29456

Ladson

30060

Marietta

30909

Augusta

31000

Clinical hospital center Osijek, Osijek

32701

Altamonte Springs

32901

Melbourne

33426

Boynton Beach

33711

St. Petersburg

33880

Winter Haven

34994

Stuart

44130

Cleveland

44136

Cleveland

45242

Cincinnati

49546

Grand Rapids

50005

Faculty Hospital Hradec Kralove, Hradec Králové

50266

West Des Moines

62500

Fakultni Nemocnice Brno, Brno

66204

Shawnee Mission

67214

Wichita

76051

Grapevine

76087

Willow Park

76100

Kaplan Medical Center, Rehovot

77030

Houston

77384

The Woodlands

77900

Fakultni nemocnice Olomouc, Olomouc

78705

Austin

79106

Amarillo

79606

Abilene

80210

Denver

84107

Salt Lake City

84132

Salt Lake City

85053

Phoenix

85704

Tucson

85710

Tucson

89052

Henderson

89502

Reno

91120

Hadassah University Hospital, Jerusalem

92093

La Jolla

92374

Redlands

92705

Santa Ana

92835

Fullerton

93720

Fresno

94040

Mountain View

95008

Campbell

95819

Sacramento

95841

Sacramento

96701

Retina Consultants of Hawaii, ‘Aiea

97221

Portland

3109601

Rambam Medical Center, Haifa

4428164

Meir Medical Center, Kfar Saba

4941492

Rabin Medical Center, Petah Tikva

6423906

Tel-Aviv Sourasky Medical Center, Tel Aviv

02114

Boston

01107

Springfield

LV1002

Pauls Stradins Clinical University Hospital, Riga

All Listed Sponsors
lead

IVERIC bio, Inc.

INDUSTRY

NCT02686658 - Zimura in Participants With Geographic Atrophy Secondary to Dry Age-Related Macular Degeneration | Biotech Hunter | Biotech Hunter