Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X Syndrome

PHASE2CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

October 31, 2017

Study Completion Date

November 30, 2017

Conditions
Fragile X Syndrome
Interventions
DRUG

Minocycline, then Minocycline/Lovastatin

Participants of this group will take 1 tablet of minocycline 50mg daily for 4 weeks, minocycline 100mg for the following 4 weeks and finally a combined treatment of minocycline 100 mg and lovastatin 40mg for the following 12 weeks.

DRUG

Lovastatin, then Minocycline/Lovastatin

Participants of this group will take 1 tablet of lovastatin 20 mg daily for 4 weeks, lovastatin 40 mg for the following 4 weeks and finally a combined treatment of minocycline 100 mg and lovastatin 40 mg for the following 12 weeks.

Trial Locations (1)

J1H 5N4

Centre de Recherche du CHUS, Sherbrooke

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

FRAXA Research Foundation

OTHER

lead

Université de Sherbrooke

OTHER