NCT02679573 - Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia | Biotech Hunter

Enrollment

860

Participants

Timeline

Start Date

December 14, 2016

Primary Completion Date

July 31, 2018

Study Completion Date

August 7, 2018

Conditions

Community Acquired Bacterial Pneumonia

Interventions

DRUG

Delafloxacin

Antibacterial agent, 300 mg IV, Q12H for at least 6 doses with potential to switch to 450 mg oral tablet, Q12H for up to 20 doses total

DRUG

Moxifloxacin

Antibacterial Agent, 400 mg IV, Q24H for at least 3 doses with potential to switch to 400 mg oral over-encapsulated tablet, Q24H for up to 10 doses total

DRUG

Linezolid

Antibacterial Agent, at local investigator discretion, subjects in the moxifloxacin arm with confirmed MRSA can switch to linezolid 600 mg IV Q12H for all remaining doses

Trial Locations (90)

14215

Melinta 306 Study Site, Buffalo

19718

Melinta 306 Study Site, Newark

21201

Melinta 306 Study Site, Baltimore

28203

Melinta 306 Study Site, Charlotte

32713

Melinta 306 Study Site, DeBary

32720

Melinta 306 Study Site, DeLand

33126

Melinta 306 Study Site, Miami

33134

Melinta 306 Study Site, Coral Gables

33185

Melinta 306 Study Site, Miami

33901

Melinta 306 Study Site, Fort Myers

36106

Melinta 306 Study Site, Montgomery

37067

Melinta 306 Study Site, Franklin

40202

Melinta 306 Study Site, Louisville

45402

Melinta 306 Study Site, Dayton

55104

Melinta 306 Study Site, Saint Paul

57702

Melinta 306 Study Site, Rapid City

59701

Melinta 306 Study Site, Butte

63110

Melinta 306 Study Site, St Louis

68124

Melinta 306 Study Site, Omaha

75110

Melinta 306 Study Site, Corsicana

71457-6215

Melinta 306 Study Site, Natchitoches

02115

Melinta 306 Study Site, Boston

01805

Melinta 306 Study Site, Burlington

07102

Melinta 306 Study Site, Newark

44106-5029

Melinta 306 Study Site, Cleveland

Unknown

Melinta 306 Study Site, Buenos Aires

Melinta 306 Study Site, Córdoba

Melinta 306 Study Site, La Plata

Melinta 306 Study Site, Pleven

Melinta 306 Study Site, Rousse

Melinta 306 Study Site, Sofia

Melinta 306 Study Site, Stara Zagora

Melinta 306 Study Site, Barranquilla

Melinta 306 Study Site, Manizales

Melinta 306 Study Site, Medellín

Melinta 306 Study Site, Quindío

Melinta 306 Study Site, Santiago de Cali

Melinta 306 Study Site, Santo Domingo

Melinta 306 Study Site, Tbilisi

Melinta 306 Study Site, Leverkusen

Melinta 306 Study Site, Munich

Melinta 306 Study Site, Budapest

Melinta 306 Study Site, Debrecen

Melinta 306 Study Site, Deszk

Melinta 306 Study Site, Miskolc

Melinta 306 Study Site, Nyíregyháza

Melinta 306 Study Site, Szombathely

Melinta 306 Study Site, Daugavpils

Melinta 306 Study Site, Liepāja

Melinta 306 Study Site, Riga

Melinta 306 Study Site, Lima

Melinta 306 Study Site, Chrzanów

Melinta 306 Study Site, Katowice

Melinta 306 Study Site, Lodz

Melinta 306 Study Site, Wroclaw

Melinta 306 Study Site, Brasov

Melinta 306 Study Site, Bucharest

Melinta 306 Study Site, Craiova

Melinta 306 Study Site, Timișoara

Melinta 306 Study Site, Arkhangelsk

Melinta 306 Study Site, Moscow

Melinta 306 Study Site, Saint Petersburg

Melinta 306 Study Site, Smolensk

Melinta 306 Study Site, Vsevolozhsk

Melinta 306 Study Site, Belgrade

Melinta 306 Study Site, Kamenitz

Melinta 306 Study Site, Kragujevac

Melinta 306 Study Site, Niš

Melinta 306 Study Site, Golnik

Melinta 306 Study Site, Ljubljana

Melinta 306 Study Site, Benoni

Melinta 306 Study Site, Chatsworth

Melinta 306 Study Site, Krugersdorp

Melinta 306 Study Site, Middelburg

Melinta 306 Study Site, Phoenix

Melinta 306 Study Site, Port Elizabeth

Melinta 306 Study Site, Pretoria

Melinta 306 Study Site, Worcester

Melinta 306 Study Site, Badalona

Melinta 306 Study Site, Barcelona

Melinta 306 Study Site, Madrid

Melinta 306 Study Site, Terrassa

Melinta 306 Study Site, Valencia

Melinta 306 Study Site, Dnipro

Melinta 306 Study Site, Kharkiv

Melinta 306 Study Site, Kyiv

Melinta 306 Study Site, Poltava

Melinta 306 Study Site, Vinnytsia

Melinta 306 Study Site, Zaporizhia

Melinta 306 Study Site, Zhytomyr