441
Participants
Start Date
February 29, 2016
Primary Completion Date
February 29, 2028
Study Completion Date
February 28, 2033
Difluoromethylornithine (DFMO)
Subjects will receive 730 Days of oral difluoromethylornithine (DFMO) at a dose of 750 mg/m2 ± 250 mg/m2 BID (strata 1, 2, 3, and 4) OR 2500 mg/m2 BID (stratum 1B) on each day of study.
RECRUITING
Penn State Milton S. Hershey Medical Center and Children's Hospital, Hershey
RECRUITING
Levine Children's Hospital, Charlotte
RECRUITING
Medical University of South Carolina, Charleston
RECRUITING
University of Florida, Gainesville
RECRUITING
Arnold Palmer Hospital for Children, Orlando
RECRUITING
St. Joseph's Children's Hospital, Tampa
RECRUITING
All Children's Hospital Johns Hopkins Medicine, St. Petersburg
RECRUITING
Monroe Carrell Jr. Children's Hospital at Vanderbilt, Nashville
ACTIVE_NOT_RECRUITING
Nationwide Children's Hospital, Columbus
RECRUITING
Helen DeVos Children's Hospital, Grand Rapids
RECRUITING
Medical College of Wisconsin, Milwaukee
RECRUITING
Children's Hospital and Clinics of Minnesota, Minneapolis
RECRUITING
Gina Martin, St Louis
RECRUITING
Children's Mercy Hospitals and Clinics, Kansas City
RECRUITING
Arkansas Children's Hospital, Little Rock
RECRUITING
Children's Medical Center, Dallas
RECRUITING
Texas Children's Cancer and Hematology Centers, Houston
RECRUITING
Dell Children's Blood and Cancer Center, Austin
RECRUITING
Primary Children's Hospital, Salt Lake City
RECRUITING
Rady Children's Hospital, San Diego
RECRUITING
Kapiolani Medical Center for Women and Children, Honolulu
RECRUITING
University of Alabama, Children's of Alabama, Birmingham
RECRUITING
UCSF Benioff Children's Hospital Oakland-, Oakland
RECRUITING
Rocky Mountain Pediatric Hematology, Denver
RECRUITING
Augusta University Health, Augusta
RECRUITING
St. Lukes, Boise
RECRUITING
Rebecca McFall, Chicago
RECRUITING
Kentucky Children's Hospital, Lexington
RECRUITING
University of Louisville, Louisville
WITHDRAWN
University of Massachusetts Medical School Worcester, Worcester
RECRUITING
Hackensack University Medical Center, Hackensack
RECRUITING
New York University, New York
RECRUITING
Duke University, Durham
RECRUITING
Cleveland Clinic Children's, Cleveland
RECRUITING
Randall Children's Hospital, Portland
RECRUITING
Hasbro Children's Hospital, Providence
RECRUITING
Children's Hospital of The King's Daughters, Norfolk
RECRUITING
Virginia Commonwealth University, Richmond
RECRUITING
Alberta Children's Hospital, Calgary
RECRUITING
CancerCare Manitoba, Winnipeg
RECRUITING
Janesway Children's Health and Rehabilitation Centre, St. John's
RECRUITING
Montreal Children's Hospital, Montreal
RECRUITING
UHC Sainte-Justine, Montreal
RECRUITING
CHUQ, Québec
RECRUITING
CIUSSS de l'Estrie-CHUS, Sherbrooke
RECRUITING
Connecticut Children's Hospital, Hartford
COMPLETED
Tufts Medical Center, Boston
Beat NB Cancer Foundation
OTHER
Team Parker for Life
UNKNOWN
Giselle Sholler
OTHER