Effect of Intraoperative Dexmedetomidine on Lung Protection Following Thoracic Aorta Surgery With Hypothermic Circulatory Arrest: a Randomized Clinical Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

February 29, 2016

Primary Completion Date

February 28, 2018

Study Completion Date

March 30, 2018

Conditions
Chronic Dissecting Aneurysm of Thoracic AortaChronic Nontraumatic Dissection of Thoracic AortaDissecting Aneurysm of the Thoracic Aorta
Interventions
DRUG

Dexmedetomidine

1ug/kg IV loading over 20 minutes followed by 0.5ug/kg/hr IV infusion until 12 hrs of aortic cross clamp off

DRUG

normal saline

IV loading and infusion of same volume of normal saline after induction until 12 hrs of aortic cross clamp off

Trial Locations (1)

Unknown

Gangnam Severance Hospital, Seoul

All Listed Sponsors
lead

Gangnam Severance Hospital

OTHER

NCT02678728 - Effect of Intraoperative Dexmedetomidine on Lung Protection Following Thoracic Aorta Surgery With Hypothermic Circulatory Arrest: a Randomized Clinical Trial | Biotech Hunter | Biotech Hunter