360
Participants
Start Date
February 29, 2016
Primary Completion Date
July 28, 2022
Study Completion Date
December 31, 2026
Open, Robotic, or Laparoscopic
Sacral Colpopexy is a surgery performed either through an incision in the abdomen or through several small incisions with the help of a laparoscope (a slender tube) or robot. The surgery is done with a permanent synthetic (man-made) mesh. The mesh is sutured (stitched) to the vagina and sacrum (tail bone) and is used as reinforcement. It provides additional support to weakened tissues and/or muscles.
Transvaginal Native Tissue Repair
Transvaginal Native Tissue Repair is a surgery performed with an incision through the vagina (transvaginal). The surgery is done using both permanent and absorbable sutures (stitches), to support weakened tissue and/or muscles, and attach the top of the vagina to ligaments in the pelvis (either to the sacrospinous ligament or uterosacral ligament).
Uphold™ LITE
Transvaginal Mesh Repair is a surgery performed with an incision through the vagina (transvaginal). The surgery is done with a permanent synthetic (man-made) mesh. The mesh is attached to ligaments in the pelvis and is used to reinforce natural tissue and/or muscles, which are no longer able to provide support to the vagina.
University of Pittsburgh, Pittsburgh
University of Pennsylvania, Philadelphia
Duke University, Durham
University of Alabama at Birmingham, Birmingham
Cleveland Clinic, Cleveland
University of Texas Southwestern Medical Center, Dallas
University of New Mexico, Albuquerque
University of California at San Diego, San Diego
Kaiser Permanente, San Diego
Brown/Women and Infants Hospital of Rhode Island, Providence
Collaborators (1)
The Cleveland Clinic
OTHER
University of Alabama at Birmingham
OTHER
University of California, San Diego
OTHER
Duke University
OTHER
University of New Mexico
OTHER
Women and Infants Hospital of Rhode Island
OTHER
RTI International
OTHER
University of Pennsylvania
OTHER
University of Pittsburgh
OTHER
Kaiser Permanente
OTHER
University of Texas Southwestern Medical Center
OTHER
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
NICHD Pelvic Floor Disorders Network
NETWORK