Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial

NACompletedINTERVENTIONAL
Enrollment

45

Participants

Timeline

Start Date

March 31, 2016

Primary Completion Date

February 28, 2017

Study Completion Date

April 1, 2019

Conditions
Persistent Organic PollutantsEndocrine Disrupting ChemicalsEndocrine Disruptor Effects
Interventions
OTHER

Whole Nuts

Participants will be advised on maintaining an iso-caloric diet. Aside consuming nuts, the remaining composition of the prescribed diet will be based on individual preferences. During the 6-month intervention, study subjects will meet with study staff every 2-3 weeks to weigh in, pick up food supplies and complete a questionnaire on compliance. All participants will have contact with the project coordinator/study dietitian a minimum of every 1-2 weeks either in-person, telephone, email and text message contacts for support, behavioral guidance and strategies. Both walnuts and almonds will be provided to participants in the whole nut study arm.

OTHER

Olestra: Fat Free Pringles

Participants will be advised on maintaining an iso-caloric diet. Aside consuming fat free potato crisps, the remaining composition of the prescribed diet will be based on individual preferences. During the 6-month intervention, study subjects will meet with study staff every 2-3 weeks to weigh in, pick up food supplies and complete a questionnaire on compliance. All participants will have contact with the project coordinator/study dietitian a minimum of every 1-2 weeks either in-person, telephone, email and text message contacts for support, behavioral guidance and strategies. Fat Free Pringles will be provided to participants in the olestra study arm.

OTHER

Vegetable Oil: Original Pringles

Participants will be advised on maintaining an iso-caloric diet. Aside consuming potato crisps, the remaining composition of the prescribed diet will be based on individual preferences. During the 6-month intervention, study subjects will meet with study staff every 2-3 weeks to weigh in, pick up food supplies and complete a questionnaire on compliance. All participants will have contact with the project coordinator/study dietitian a minimum of every 1-2 weeks either in-person, telephone, email and text message contacts for support, behavioral guidance and strategies. Original Pringles will be provided to participants in the vegetable oil study arm.

Trial Locations (1)

92093

UCSD Moores Cancer Center, La Jolla

All Listed Sponsors
collaborator

San Diego State University

OTHER

lead

University of California, San Diego

OTHER

NCT02675101 - Nuts and Olestra for Persistent Organic Pollutant Reduction (NO-POPs) Trial | Biotech Hunter | Biotech Hunter