Stimulating Language in Subacute StrokE

NACompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

June 15, 2016

Primary Completion Date

November 12, 2021

Study Completion Date

April 1, 2022

Conditions
Stroke
Interventions
DEVICE

A-tDCS (1 mA)

1 mA of A-tDCS stimulation is induced between two 5 cm x 5 cm saline soaked sponges where one sponge (anode: A-tDCS) is placed on the scalp over the targeted cortical region. Ramping up of the current to 1 mA occurs over 10-15 seconds to allow participants to habituate to the tingling sensation. A-tDCS stimulation will be active only in the first 20 minutes of the 45-minute treatment session.

BEHAVIORAL

SALT

Computer-delivered naming treatment requires matching word (heard and seen being produced by the speaker) with pictures depicting common objects. It is run on a laptop computer with headphones and 2 large response buttons. During treatment, a picture appears on the laptop screen for 2 seconds. Then, a video of the speaker's face below the nose is presented on the screen saying a word that either matches or does not match the picture. The participant is instructed to press a green response button if the word matches the picture and press the red response button if the word does not match the picture.

DEVICE

Sham

1 mA of A-tDCS stimulation is induced between two 5 cm x 5 cm saline soaked sponges where one sponge (anode: A-tDCS) is placed on the scalp over the targeted cortical region. Ramping up of the current to 1 mA occurs over 10-15 seconds to allow participants to habituate to the tingling sensation. Then, the current will be ramped back down to 0 mA in the sham condition. Termination of the stimulation after the ramping up process is generally undetectable, and the brief duration of stimulation yields no functional effects.

Trial Locations (1)

21205

Johns Hopkins Hospital, Baltimore

All Listed Sponsors
collaborator

University of South Carolina

OTHER

lead

Johns Hopkins University

OTHER

NCT02674490 - Stimulating Language in Subacute StrokE | Biotech Hunter | Biotech Hunter