NCT02671903 - The His Optimised Pacing Evaluated for Heart Failure Trial (HOPE-HF). | Biotech Hunter

Enrollment

198

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

October 31, 2020

Study Completion Date

October 31, 2020

Conditions

Heart Failure

Interventions

DEVICE

Pacemaker: AV optimised, His pacing.

Direct His bundle pacing: a Medtronic Select Secure 3830 pacing lead will be positioned at the His bundle. If selective direct His bundle pacing cannot be achieved then non-selective His bundle pacing will be accepted. AV delay optimisation: will be performed using acute non-invasive blood pressure acquired using the Finometer device (Finapres Medical systems, Netherlands).

Trial Locations (15)

WD18 0HB

West Hertfordshire Hospitals NHS Trust, Watford

Unknown

Basildon and Thurrock Hospitals NHS Foundation Trust, Basildon

University Hospitals Birmingham NHS Foundation Trust, Birmingham

University Hospitals Bristol NHS Foundation Trust, Bristol

Western Sussex Hospitals NHS Foundation Trust, Chichester

Medway NHS Foundation Trust, Gillingham

University Hospitals of Leicester NHS Trust, Leicester

Barts Health NHS Trust, London

Guy's and St Thomas' NHS Foundation Trust, London

King's College Hospital NHS Foundation Trust, London

Royal Brompton & Harefield NHS Foundation Trust, London

Papworth Hospital NHS Foundation Trust, Papworth Everard

Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield

Great Western Hospitals NHS Foundation Trust, Swindon

W12 0HS

Hammersmith Hospital, London