Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology

PHASE4CompletedINTERVENTIONAL
Enrollment

131

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

May 31, 2016

Study Completion Date

July 31, 2016

Conditions
Hemorrhage
Interventions
DRUG

Tranexamic Acid

Tranexamic acid (TXA) is a synthetic analog of serin than reversibly inhibits fibrinolysis by blocking lysine union sites in the plasmin and plasminogen activator molecules. TXA: bolus of 10 mg/kg thirty minutes before resection followed by infusion of 1 mg/kg/h intraoperatively and for 24 h postoperatively

DRUG

Placebo

An equal volume of saline

Trial Locations (1)

1006

Ali JENDOUBI, Tunis

All Listed Sponsors
lead

University Tunis El Manar

OTHER

NCT02653261 - Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology | Biotech Hunter | Biotech Hunter