TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes.

PHASE4CompletedINTERVENTIONAL
Enrollment

525

Participants

Timeline

Start Date

November 1, 2016

Primary Completion Date

January 31, 2021

Study Completion Date

January 31, 2021

Conditions
Type 2 Diabetes
Interventions
DRUG

Sitagliptin - DPP4i

DPP4 inhibitor 100mg supplied as over-encapsulated hard capsule shell to be taken orally, once a day for 16 weeks in addition to existing prescribed oral diabetes therapy.

DRUG

Canagliflozin - SGLT2i

SGLT2 inhibitor 100mg supplied as over-encapsulated hard capsule shell to be taken orally, once a day for 16 weeks in addition to existing prescribed oral diabetes therapy.

DRUG

Pioglitazone - TZD

Thiazolidinedione 30mg supplied as over-encapsulated hard capsule shell to be taken orally, once a day for 16 weeks in addition to existing prescribed oral diabetes therapy.

Trial Locations (1)

EX2 5DW

Exeter Clinical Research Facility, Exeter

All Listed Sponsors
lead

Royal Devon and Exeter NHS Foundation Trust

OTHER

collaborator

University of Exeter

OTHER

collaborator

NHS Tayside

OTHER_GOV

collaborator

University of Dundee

OTHER

collaborator

University of Glasgow

OTHER

collaborator

Newcastle University

OTHER

collaborator

King's College London

OTHER

NCT02653209 - TriMaster: Study of a DPP4 Inhibitor, SGLT2 Inhibitor and Thiazolidinedione as Third Line Therapy in Patients With Type 2 Diabetes. | Biotech Hunter | Biotech Hunter