Initiation of Long-term Non-invasive Ventilation in COPD

NACompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

July 25, 2018

Study Completion Date

July 25, 2018

Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DEVICE

Transcutaneous measurements of PCO2

PCO2 will be measured transcutaneously with an ear lobe sensor before initiation of NIV, and during the initiation period (SenTec DM®, Software V-STATS 4.0; SenTec AG; Therwil, Switzerland)

DEVICE

Telemonitoring

Telemonitoring will be used to send data from the transcutaneous measurements, data from the EMG measurements and data from the ventilator from home to the hospital.

DEVICE

EMG

Surface EMG of the respiratory muscles will be used to monit patients in both groups as a surrogate marker of respiratory muscle unloading and to detect PVA during NIV

OTHER

Home initiation of NIV

The primary aim of the study is to compare home and inhospital initiation of NIV

OTHER

Inhospital initiation of NIV

The primary aim of the study is to compare home and inhospital initiation of NIV

Trial Locations (1)

9700 RB

University Medical Center Groningen, Groningen

All Listed Sponsors
lead

University Medical Center Groningen

OTHER

NCT02652559 - Initiation of Long-term Non-invasive Ventilation in COPD | Biotech Hunter | Biotech Hunter