40
Participants
Start Date
February 29, 2016
Primary Completion Date
October 31, 2016
Study Completion Date
October 31, 2016
Dexmedetomidine
A maintenance dose of Dexmedetomidine infusion at 0.5 mcg/kg/hour made to 20 mL with normal saline will be administered
Placebo
A maintenance dose of 20 mL with normal saline will be administered at a rate similar to that of dexmedetomidine
Ondansetron
0.15 mg/kg intravenous (IV) will be given as a pre-medication
fentanyl
1.5 μg/kg intraoperative
propofol
10 mg every 5 seconds until the BIS level dropped below 60 for induction of anesthesia
Atracurium
0.5 mg/kg IV for endotracheal intubation
diclofenac sodium
1 mg/kg for postoperative analgesia
desflurane
1 MAC concentration (expired fraction of 6.0 vol%) for maintenance of anesthesia
Theodor Bilharz Research Institute, Giza
Theodor Bilharz Research Institute
OTHER