Dexmedetomidine and Desflurane Consumption

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

February 29, 2016

Primary Completion Date

October 31, 2016

Study Completion Date

October 31, 2016

Conditions
Anesthesia
Interventions
DRUG

Dexmedetomidine

A maintenance dose of Dexmedetomidine infusion at 0.5 mcg/kg/hour made to 20 mL with normal saline will be administered

DRUG

Placebo

A maintenance dose of 20 mL with normal saline will be administered at a rate similar to that of dexmedetomidine

PROCEDURE

Ondansetron

0.15 mg/kg intravenous (IV) will be given as a pre-medication

PROCEDURE

fentanyl

1.5 μg/kg intraoperative

PROCEDURE

propofol

10 mg every 5 seconds until the BIS level dropped below 60 for induction of anesthesia

PROCEDURE

Atracurium

0.5 mg/kg IV for endotracheal intubation

PROCEDURE

diclofenac sodium

1 mg/kg for postoperative analgesia

PROCEDURE

desflurane

1 MAC concentration (expired fraction of 6.0 vol%) for maintenance of anesthesia

Trial Locations (1)

12411

Theodor Bilharz Research Institute, Giza

All Listed Sponsors
lead

Theodor Bilharz Research Institute

OTHER

NCT02652312 - Dexmedetomidine and Desflurane Consumption | Biotech Hunter | Biotech Hunter