Cutaneous Microcirculation and Nervous Sensitivity in Psoriasis

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

February 8, 2016

Primary Completion Date

July 16, 2018

Study Completion Date

July 16, 2018

Conditions
Psoriasis
Interventions
OTHER

Acetylcholine iontophoresis

Acetylcholine will be locally delivered to patients by iontophoresis successively on healthy skin and on psoriasis plaque (order determined by randomization).

OTHER

Sodium Nitroprussiate iontophoresis

Sodium Nitroprussiate will be locally delivered to patients by iontophoresis successively on healthy skin and on psoriasis plaque (order determined by randomization).

OTHER

ppi water iontophoresis

ppi water will be locally delivered to patients by iontophoresis successively on healthy skin and on psoriasis plaque (order determined by randomization).

OTHER

Laser Doppler recording

Skin blood flow will be recorded by laser Doppler during 2 minutes before iontophoresis, and during 30 minutes following iontophoretic delivery of vasodilators.

Trial Locations (1)

69437

Hôpital Edouard Herriot - Service de Dermatologie et Vénéréologie, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT02652065 - Cutaneous Microcirculation and Nervous Sensitivity in Psoriasis | Biotech Hunter | Biotech Hunter