Cavity Shaving in Breast Conserving Surgery for Breast Cancer Patients

NACompletedINTERVENTIONAL
Enrollment

181

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

November 30, 2018

Study Completion Date

August 20, 2019

Conditions
Breast Cancer
Interventions
PROCEDURE

Cavity shaving

Resect the residual cavity circumferentially (superior, inferior, medial, lateral) and the thickness of the cavity shaving depends on the surgeon's discretion (Recommended 0.5-1.0cm). The principles of the cavity shaving includes: 1) do not compromise the cosmetic outcomes; 2) covers the entire cavity;

PROCEDURE

Standardized BCS+CM assessment.

For standardized BCS(Chen K, et al. Ann Surg Oncol. 2012), we resect a rim of 1 cm macroscopically normal tissue around the tumor. The anterior and posterior margins of the tumor-containing specimen extended up to the subdermal plane of the skin and down to the pectoralis major fascia, respectively. The anterior and posterior CMs assessment will not be needed. A surgical blade was used for resecting the CMs (superior, inferior, medial and lateral) to render the thickness of the CMs as thin as possible. No procedures were required for distinguishing the inner and outer surface. They were then frozen and cut parallel, but not perpendicular to the largest surface area. CMs were defined as positive when in situ or invasive carcinoma was found intraoperatively by frozen-section analysis.

Trial Locations (1)

510120

Sun-Yat-Sen Memorial Hospital of Sun-Yat-Sen University, Guangzhou

All Listed Sponsors
lead

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

OTHER

NCT02648802 - Cavity Shaving in Breast Conserving Surgery for Breast Cancer Patients | Biotech Hunter | Biotech Hunter