77
Participants
Start Date
June 30, 2016
Primary Completion Date
August 17, 2020
Study Completion Date
August 17, 2020
Placebo
A matched placebo will be given once daily for 12 months.
Candesartan
Candesartan will be started at 8 mg orally, once daily. The dose will be increased in 2 week increments to 16 mg and 32 mg orally, once a day, as long as SBP\>100 mm Hg, DBP\>40 mm Hg and there are no reported symptoms of hypotension (dizziness or weakness). Candesartan will be given for a total of 12 months.
Emory University, Atlanta
Wesley Woods Center, Atlanta
National Institute on Aging (NIA)
NIH
Emory University
OTHER