NCT02645565View on ClinicalTrials.gov

Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis

PHASE4CompletedINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

December 31, 2015

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Lupus Nephritis
Interventions
DRUG

Cyclophosphamide

Cyclophosphamide is an alkylating agent used for the treatment of lupus nephritis.

DRUG

Azathioprine

azathioprine will be given at 2 mg/kg.

DRUG

Methylprednisolone

Each treatment arm shall receive 1 gm methylprednisolone pulse for 3 days followed by prednisolone 1 mg/kg for 4 weeks and tapered 5 mg every 2 weekly ,to maintain 7.5 mg dose daily

Trial Locations (1)

605006

Department of Clinical Immunology , Jawaharlal Institute of Post graduate Medical Educationa and Research, Puducherry

All Listed Sponsors
lead

Jawaharlal Institute of Postgraduate Medical Education & Research

OTHER_GOV

NCT02645565 - Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis | Biotech Hunter | Biotech Hunter