A Study of CK-2127107 in Patients With Spinal Muscular Atrophy

PHASE2CompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 14, 2016

Primary Completion Date

May 31, 2018

Study Completion Date

May 31, 2018

Conditions
Spinal Muscular Atrophy
Interventions
DRUG

Placebo

Granules for oral suspension (placebo)

DRUG

Reldesemtiv 150 mg

Granules for oral suspension, 18.7% reldesemtiv

DRUG

Reldesemtiv 450 mg

Granules for oral suspension, 56.0% reldesemtiv

Trial Locations (19)

19104

Children's Hospital of Philadelphia, Philadelphia

21287

Johns Hopkins Hospital Institute for Clinical and Translational Research Pediatric Clinical Research Unit, Baltimore

27705

Duke University Medical Center, Durham

32827

Nemours Childrens Hospital, Orlando

43210

The Ohio State University Wexner Medical Center, Columbus

60611

Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago

63110

Washington University School of Medicine, St Louis

66160

University of Kansas Medical Center, Kansas City

80045

Children's Hospital Colorado, Aurora

84132

The University of Utah, Clinical Neurosciences Center, Salt Lake City

90095

UCLA, Los Angeles

92868

University of California Irvine, Orange

94304

Pediatric Neuromuscular Clinic Stanford University, Palo Alto

06053

Hospital for Special Care, New Britain

02115

Boston Children's Hospital, Boston

T3B 6A8

Alberta Children's Hospital, Calgary

V6H 3V4

Children's and Women's Health Centre of British Columbia, Vancouver

N6A 4G5

Children's Hospital - LHSC, London

H3A 2B4

Montreal Neurological Institute and Hospital, Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Astellas Pharma Global Development, Inc.

INDUSTRY

lead

Cytokinetics

INDUSTRY

NCT02644668 - A Study of CK-2127107 in Patients With Spinal Muscular Atrophy | Biotech Hunter | Biotech Hunter