Can Acupuncture Treat Post-stroke Depression?

NACompletedINTERVENTIONAL
Enrollment

91

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

July 31, 2018

Study Completion Date

October 31, 2018

Conditions
StrokeDepressionStroke Sequelae
Interventions
PROCEDURE

Dense cranial electroacupuncture stimulation

"DCEAS is a novel stimulation mode in which electrical stimulation is delivered on acupoints located on the forehead.~Six pairs of acupoints are used: Baihui (GV20, +) and Yintang (EX-HN3, -), left Sishencong (EX-HN1, -) and Toulinqi (GB15, +), right Sishencong (EX-HN1, -) and Toulinqi (GB15, +), bilateral Shuaigu (GB8, L+, R-), bilateral Taiyang (EX-HN5, L+, R-), and bilateral Touwei (ST8, L+, R-).~Disposable acupuncture needles (Hwato®, 0.30 mm in diameter and 25-40 mm in length) are inserted at a depth of 10-30 mm perpendicularly or obliquely into acupoints. Manual manipulation is then conducted to evoke needling sensation, followed by electrical stimulation (ITO ES-160, continuous waves at 2 Hz, 100 µs)."

PROCEDURE

Body acupuncture

"Following acupoints are used: Shui-Gou (GV26), Shen-Men (HT7). He-Gu (LI4), Qu-Chi (LI11), Guan-Yuan (CV4), Zu-San-Li (ST36), Feng-Long (ST40) and San-Yin-Jiao (SP6).~Disposable acupuncture needles (Hwato®, 0.30 mm in diameter and 25-40 mm in length) are inserted at a depth of 10-30 mm perpendicularly or obliquely into acupoints. Manual manipulation is then conducted to evoke needling sensation at 15 min. No electrical stimulation is delivered."

DRUG

Antidepressant

Patients will continue their existing antidepressant therapy as usual. Treatment regimens may be further adjusted during 8 weeks of study, depending upon physicians' discretion.

OTHER

Rehabilitation

Patients will continue their existing rehabilitation therapy as usual. Treatment regimens may be further adjusted during 8 weeks of study, depending upon physicians' discretion.

PROCEDURE

Least acupuncture stimulation

The acupoints chosen are less related to the treated syndromes based on Traditional Chinese Medicine (TCM) theory; the number of acupoints used and the intensity of electrical stimulation are also lower than the comprehensive acupuncture regimen. The following 6 acupoints will be used in LAS control: bilateral Tong-Tian (BI7, L+, R-), bilateral Shou San-Li (LI10) and bilateral Fu-Yang (BL59). Electrical stimulation will be only performed on bilateral Tong-Tian (BI7) and the intensities are adjusted to a level at which patients just start feeling the stimulation.

Trial Locations (2)

Unknown

Department of Rehabilitation, Kowloon Hospital, Kowloon

Division of Rehabilitation Medicine, Tung Wah Hospital., Sheung Wan

All Listed Sponsors
collaborator

Tung Wah Hospital

OTHER

collaborator

Kowloon Hospital, Hong Kong

OTHER

lead

The University of Hong Kong

OTHER

NCT02644161 - Can Acupuncture Treat Post-stroke Depression? | Biotech Hunter | Biotech Hunter