Does Bicarbonate in Addition to Theophylline Reduce CIN?

NACompletedINTERVENTIONAL
Enrollment

152

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

June 30, 2012

Study Completion Date

December 31, 2012

Conditions
Radiographic Contrast Agent Nephropathy
Interventions
OTHER

Hydration with bicarbonate in addition to theophylline

0.154-molar sodium bicarbonate; 3 ml per kg bodyweight (maximum 330 ml) one hour before contrast exposure; additionally 200 mg theophylline as a short infusion; after contrast application hydration with another 1 ml per kg bodyweight per hour (maximum 110 ml per hour) for 6 hours

OTHER

Hydration with sodium chloride in addition to theophylline

0.9% sodium chloride; 3 ml per kg bodyweight (maximum 330 ml) one hour before contrast exposure; additionally 200 mg theophylline as a short infusion; after contrast application hydration with another 1 ml per kg bodyweight per hour (maximum 110 ml per hour) for 6 hours

All Listed Sponsors
lead

Technical University of Munich

OTHER

NCT02643602 - Does Bicarbonate in Addition to Theophylline Reduce CIN? | Biotech Hunter | Biotech Hunter