Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial

PHASE4CompletedINTERVENTIONAL
Enrollment

801

Participants

Timeline

Start Date

June 6, 2016

Primary Completion Date

December 1, 2020

Study Completion Date

December 1, 2020

Conditions
Cardiopulmonary ArrestRespiratory Arrest
Interventions
DRUG

Etomidate

Patients randomized to this group will receive etomidate immediately prior to emergency endotracheal intubation.

DRUG

Ketamine

Patients randomized to this group will receive ketamine immediately prior to emergency endotracheal intubation.

PROCEDURE

Emergency Endotracheal Intubation

Patients enrolled in the study will be endotracheally intubated. (A breathing tube will be placed into the patient's mouth and trachea). This procedure is being done as part of standard emergency care. Standard endotracheal tubes will be used. Our hospital uses primarily Mallinckrodt (TM) brand endotracheal tubes.

DEVICE

Mechanical Ventilation

Patients enrolled in the study will be mechanically ventilated, using a standard ventilator used in our hospital. The mechanical ventilator is attached to the patient's endotracheal tube and helps sustain the patient's life. Our hospital uses several brands of mechanical ventilators.

Trial Locations (1)

75235

Parkland Hospital, Dallas

All Listed Sponsors
lead

University of Texas Southwestern Medical Center

OTHER

NCT02643381 - Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial | Biotech Hunter | Biotech Hunter