Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study

NACompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

February 18, 2016

Primary Completion Date

June 14, 2019

Study Completion Date

June 14, 2019

Conditions
SchizophreniaSchizoaffective DisorderBipolar Disorder I
Interventions
DEVICE

Excitatory TMS

Single session of intermittent theta-burst stimulation (600 pulses in blocks of 2s, separated by 8s of pause) to cerebellar vermis.

DEVICE

Inhibitory TMS

Single session of continuous theta-burst stimulation of 600 pulses to cerebellar vermis.

DEVICE

Sham TMS

Single session, using the exact same procedures as the active arms but with a sham coil, which is designed to induce the same nonspecific sensory effects of TMS (auditory and somatosensory activation) without inducing the neuromodulatory magnetic fields.

Trial Locations (2)

02478

McLean Hospital, Belmont

02129

Massachusetts General Hospital, Charlestown

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

lead

Mclean Hospital

OTHER

NCT02642029 - Targeting Cerebellum to Treat Psychosis: a Transcranial Magnetic Stimulation (TMS) Study | Biotech Hunter | Biotech Hunter