NCT02635386 - EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS) | Biotech Hunter

Enrollment

119

Participants

Timeline

Start Date

March 22, 2016

Primary Completion Date

July 22, 2020

Study Completion Date

October 9, 2020

Conditions

Polycystic Ovary SyndromeObesity

Interventions

DRUG

Exenatide once weekly (EQW )

2 mg SC injection every 7 days

DRUG

Dapagliflozin (DAPA)

One pill (10 mg) by mouth daily (QD) in am

DRUG

EQW plus DAPA

2 mg SC injection every 7 days One pill (10 mg) by mouth QD in am

DRUG

Dapagliflozin plus Glucophage (MET ER)

DAPA/MET ER-5 mg /1000 mg - 1 pill by mouth in am with food for 4 weeks DAPA/MET ER-10 mg /2000 mg - 2 pills in am by mouth with food -final dose

DRUG

Phentermine /Topiramate (PHEN/ TPM) ER

PHEN 3.75/TPM ER 23mg - 1 pill by mouth once daily in am for 2 weeks. After 2 weeks, PHEN 7.5mg/TPM ER 46mg- 1 pill by mouth once daily in am

Trial Locations (1)

Woman's Hospital, Baton Rouge