ART Drug Dosage Adjustment in HIV-infected Population

PHASE4CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

April 30, 2015

Primary Completion Date

December 31, 2016

Conditions
HIV Infections
Interventions
DRUG

Tenofovir(TDF)+Lamivudine(3TC)+Efavirenz(EFV)

The first 2 weeks, TDF (300 mg) + 3-TC (300 mg) + EFV (400 mg); week 3, TDF (200 mg) + 3-TC (300 mg) + EFV (400 mg ); week 4, TDF (150 mg) + 3-TC (300 mg) + EFV (400 mg).From week5, if the HIV viral load decreased as expected or no rebound, use TDF (200 mg) + 3-TC (300 mg) + EFV (400 mg) until study complete; if the viral load increases, switch to the standard treatment regimen: TDF (300 mg) + 3-TC (300 mg) + EFV (600 mg).

Trial Locations (1)

201508

Shanghai Public Health Clinical Center, Shanghai

All Listed Sponsors
lead

Shanghai Public Health Clinical Center

OTHER_GOV

NCT02632474 - ART Drug Dosage Adjustment in HIV-infected Population | Biotech Hunter | Biotech Hunter