Enhanced CJD Surveillance in the Older Population

CompletedOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

January 19, 2016

Primary Completion Date

March 31, 2022

Study Completion Date

March 31, 2022

Conditions
Prion DiseaseDementia
Interventions
OTHER

Medical history questionnaire

Epidemiological review of past medical/dental history; residential history; occupational history; family history of neurodegenerative disease.

OTHER

Clinical assessment and review

History of current illness; neurological examination including general appearance, full cognitive assessment and physical examination; MRI research brain scan.

OTHER

Participant follow-up

Hospital patient management system; regular telephone contact with patient/representative.

OTHER

Blood or buccal sample

Codon-129 genotyping; storage for future research.

OTHER

Post mortem examination

Brain tissue donation to the Edinburgh Brain and Tissue Bank for research,including investigations for evidence of prion disease.

Trial Locations (1)

EH4 2XU

CJD Research and Surveillance Unit, Western General Hospital, Edinburgh

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

collaborator

Department of Health, United Kingdom

OTHER_GOV

lead

University of Edinburgh

OTHER

NCT02629640 - Enhanced CJD Surveillance in the Older Population | Biotech Hunter | Biotech Hunter