HDR Brachytherapy vs. LDR Brachytherapy Monotherapy in Localized Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

December 31, 2017

Study Completion Date

February 28, 2021

Conditions
Prostate Cancer
Interventions
RADIATION

Permanent Iodine-125 seed implant

"Permanent Iodine seed implant is performed under general or epidural anesthesia with the patient is positioned in the lithotomy position.~A Foley catheter is inserted in the bladder. Under transrectal ultrasound guidance, the prostates is scanned and the dosimetry is generated. Catheters are inserted in the prostate and the seeds are injected using the Nucletron automatic after loader according to the dosimetry plan.~The catheters are removed at the end of the procedure."

RADIATION

High-Dose-rate Prostate Brachytherapy

"High-Dose-Rate Prostate brachytherapy is performed under general or epidural anesthesia, the patient is positioned in the lithotomy position.~A Foley catheter is inserted in the bladder. Under transrectal ultrasound guidance, catheters are inserted in the prostate to assure adequate coverage. The patient is returned in dorsal decubitus and a CT scan or Ultrasound scan is performed. A inverse-planning dosimetry plan is generated to deliver 19 Gy to the target volume. The patient is treated and then the implant is removed and anesthesia is reversed."

Trial Locations (1)

G1R 2J6

CHU de Québec- L'Hôtel-Dieu de Québec, Québec

All Listed Sponsors
collaborator

Université de Montréal

OTHER

collaborator

Sunnybrook Health Sciences Centre

OTHER

lead

CHU de Quebec-Universite Laval

OTHER

NCT02628041 - HDR Brachytherapy vs. LDR Brachytherapy Monotherapy in Localized Prostate Cancer | Biotech Hunter | Biotech Hunter