NCT02624726 - Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

October 31, 2018

Study Completion Date

March 31, 2019

Conditions

Metastatic Colorectal Cancer

Interventions

DRUG

5 Fluorouracil

5 Fluorouracil: 400mg/m2, bolus infusion in \<5min followed by 5 Fluorouracil: 2400mg/m2, i.v in 46 hours continuous infusion (cycle repeated every two weeks)

DRUG

Leucovorin

Leucovorin: 400mg/m2, i.v in 2 hours infusion (cycle repeated every two weeks)

DRUG

Irinotecan

Irinotecan: 180mg/m2, i.v in 90min infusion (cycle repeated every two weeks)

DRUG

Aflibercept

Aflibercept: 4mg/kg i.v in 1 hour infusion (cycle repeated every two weeks)

Trial Locations (10)

71110

University Hospital of Heraklion Crete, Heraklion

Unknown

251 Air Forces Military Hospital of Athens, Athens

"Anicancer Hospital of Athens Agios Savvas", Athens

"Anticanscer Hospital of Athens Agios Savvas", Athens

"Athens Hospital Mitera Hygia Polis", Athens

"General Hospital of Athens Aretaieio", Athens

"General Hospital of Athens Sotiria", Athens

IASO General Hospital, Athens

University Hospital of Patras-Rio, Rio

Thessaloniki Bioclinic, Thessaloniki