Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

July 31, 2016

Study Completion Date

July 31, 2016

Conditions
Coagulation Defect; Bleeding
Interventions
DRUG

hydroxyethyl starch (6% 130/0.4)

preloaded prior to spinal anesthesia with 500 mL hydroxyethyl starch (6%130/0.4) (Voluven).

DRUG

Hyperbaric bupivacaine

Sub arachnoid 10-12 mg hyperbaric bupivacaine

DRUG

Morphine

Sub arachnoid 200 meg morphine

DRUG

Isotonic 0.9 sodium chloride (NaCl) solution

10 ml/kg of isotonic 0.9 sodium chloride (NaCl) solutions will be used as co loading during the duration of the operation

DRUG

Ephedrine

If severe hypotension (fall of \> 20% of mean arterial pressure from baseline) occurred, vasopressors, 6 mg ephedrine (per dose) will be used.

DRUG

Atropine

Bradycardia (fall of \>30% of heart rate from baseline or \<50 beats /minute and when associated with hypotension) will treated with 0.5 mg of atropine intravenous.

Trial Locations (1)

Unknown

Faculty of Medicine, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT02622126 - Colloid Pre-Loading on D-Dimer During Cesarean Section Under Spinal Anesthesia | Biotech Hunter | Biotech Hunter