FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

121

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

October 31, 2016

Study Completion Date

December 31, 2016

Conditions
HypoxiaRespiratory AcidosisModerate/Severe Respiratory Distress
Interventions
DEVICE

Treatment strategy: Non-invasive respiratory support delivered via high flow nasal cannula

A heated, humidified, HFNC device will be used to deliver a gas flow rate of 2 L/kg/min for the duration that the patient needs non-invasive respiratory support

DEVICE

Treatment strategy: Non-invasive respiratory support delivered via continuous positive airway pressure

CPAP will be provided using a set expiratory pressure of 6-8 cm water (H2O) pressure for the duration that the infant needs non-invasive respiratory support

Trial Locations (3)

Unknown

Barts Health NHS Trust, London

Great Ormond Street Hospital for Children NHS Foundation Trust, London

Imperial College Healthcare NHS Trust, London

All Listed Sponsors
collaborator

Imperial College London

OTHER

collaborator

Barts & The London NHS Trust

OTHER

collaborator

Intensive Care National Audit & Research Centre

OTHER

lead

Great Ormond Street Hospital for Children NHS Foundation Trust

OTHER

NCT02612415 - FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study | Biotech Hunter | Biotech Hunter