Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

67

Participants

Timeline

Start Date

March 21, 2016

Primary Completion Date

May 16, 2018

Study Completion Date

May 16, 2018

Conditions
Eosinophilic EsophagitisEosinophilic Gastrointestinal Disorders (EGIDs)
Interventions
OTHER

1 Food Elimination Diet

Participants eliminate milk from the diet for 12 weeks

OTHER

4 Food Elimination Diet

Participants eliminate milk, egg, wheat, soy from the diet for 12 weeks

OTHER

4 Food Elimination Diet (post 1FED failure)

Participants that fail to respond to 1FED in phase 1 eliminate milk, egg, wheat, soy from the diet for 12 weeks in Phase 2

DRUG

Fluticasone Propionate, 800 mcg twice daily (post 4FED failure)

Participants that fail to respond to 4FED in phase 1 administer swallowed glucocorticosteroids (Flovent HFA) 800 mcg twice daily for 12 weeks in Phase 2

Trial Locations (1)

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

lead

Children's Hospital Medical Center, Cincinnati

OTHER

NCT02610816 - Eosinophilic Esophagitis Intervention Trial-1 Food vs. 4 Food Elimination Diet Followed by Swallowed Glucocorticoids | Biotech Hunter | Biotech Hunter