Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia

Each patient in the treatment group will receive 400 units of botulinum toxin. 100 units will be injected at adductors at each leg and 100 units will be applied in each triceps surae bilaterally.

Each patient in the placebo group will receive sterile sodium chloride injections at adductors and triceps surae muscles bilaterally.