Phenytoin for Memory Impairment Secondary to Megestrol

PHASE4CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

July 31, 2015

Primary Completion Date

November 30, 2016

Study Completion Date

December 31, 2016

Conditions
Cognitive Impairment
Interventions
DRUG

Phenytoin 200 mg capsule

Phenytoin oral capsule was initiated on Day 1 and administered at 200 mg twice/day for four consecutive days (Days 1 - 4).

DRUG

Megestrol 800 mg liquid

Liquid megestrol 800 mg/was initiated on Day 2 and administered at 09:00 for three consecutive days (Days 2 - 4).

DRUG

Phenytoin-matched Placebo capsule

Phenytoin-matched oral Placebo capsule was initiated on Day 1 and administered for four consecutive days (Days 1 - 4).

DRUG

Megestrol-matched liquid Placebo

Megestrol-matched liquid placebo was initiated on Day 2 and administered at 09:00 for three consecutive days (Days 2 - 4).

Trial Locations (1)

75390

UT Southwestern Medical Center, Dallas

All Listed Sponsors
collaborator

The Rogosin Institute

OTHER

lead

University of Texas Southwestern Medical Center

OTHER

NCT02595723 - Phenytoin for Memory Impairment Secondary to Megestrol | Biotech Hunter | Biotech Hunter