Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy

PHASE2CompletedINTERVENTIONAL
Enrollment

412

Participants

Timeline

Start Date

June 1, 2016

Primary Completion Date

July 3, 2018

Study Completion Date

July 30, 2018

Conditions
HemorrhageCoagulopathyTrauma
Interventions
DEVICE

VHA algorithm

Analysis of more than 2,200 trauma subjects has enabled the definition of clinically-relevant VHA thresholds (i.e. ROTEM® and TEG® parameters) and patterns by which it is possible to rapidly identify coagulopathic patients and anticipate the need for massive transfusion. These threshold parameters have been defined and applied to the generation of an evidence-based targeted treatment algorithm (i.e. the Intervention)

Trial Locations (7)

Unknown

Copenhagen University Hospital, Copenhagen

Kliniken der Stadt Köln gGmbH, Cologne

Academic Medical Centre, Amsterdam

Oslo University Hospital, Oslo

Queens Medical Centre, Nottingham

John Radcliffe Hospital, Oxford

E1 1BB

The Royal London Hospital, London

All Listed Sponsors
collaborator

Oslo University Hospital

OTHER

collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

collaborator

Klinikum der Universität Köln

OTHER

collaborator

Rigshospitalet, Denmark

OTHER

collaborator

Oxford University Hospitals NHS Trust

OTHER

collaborator

Barts & The London NHS Trust

OTHER

collaborator

European Commission

OTHER

lead

Queen Mary University of London

OTHER

NCT02593877 - Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy | Biotech Hunter | Biotech Hunter