Start Date
Not specified
Deflazacort
Deflazacort, a glucocorticoid with anti-inflammatory and immunosuppressive effects, is used in treating a variety of diseases. Pharmacologically it is an inactive pro-drug which is metabolized immediately to the active metabolite, 21 desacetyl-DFZ. The elimination of this metabolite is primarily via the urine in humans. Its potency is approximately 70 to 90% of prednisone and 6 mg of deflazacort has approximately the same anti-inflammatory potency as 5 mg of prednisolone or prednisone.
Children's Hospital of Pittsburgh of UPMC, Pittsburgh
Penn State Milton S. Hershey Medical Center, Hershey
Children's National Medical Center, Washington D.C.
Kennedy Krieger Institute, Baltimore
University of Virginia Children's Hospital, Charlottesville
Virginia Commonwealth University, Richmond
Children's Specialty Group, Norfolk
Wake Forest School of Medicine, Winston-Salem
Neurosciences Institute, Neurology-Charlotte, Charlotte
Greenville Health System, Greenville
Children's Healthcare of Atlanta- Scottish Rite, Atlanta
University of Florida Clinical Research Center, Gainesville
Nicklaus Children's Hospital, Miami
Shriner's Hospital for Children - Tampa, Tampa
Vanderbilt University Medical Center, Nashville
Wesley Neurology Clinic, Cordova
Riley Hospital for Children at IU Health, Indianapolis
University of Michigan Health System, Ann Arbor
Wayne State University- Children's Hospital of Michigan, Detroit
Helen DeVos Children's Hospital Neurology Clinic, Grand Rapids
University of Iowa Hospitals and Clinics, Iowa City
Gillette Children's Specialty Healthcare, Saint Paul
Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Rush University Medical Center, Chicago
Shriner's Hospital for Children - Chicago, Chicago
Carle Foundation Hospital, Urbana
University of Kansas Medical Center, Kansas City
Arkansas Children's Hospital, Little Rock
Children's Medical Center, Dallas
Cook Children's Medical Center, Fort Worth
Texas Children's Hospital, Houston
University of Texas Health Science Center - San Antonio, San Antonio
Children's Hospital Colorado, Aurora
Phoenix Children's Hospital, Phoenix
Las Vegas Clinic, Las Vegas
UCLA Health, Los Angeles
Childrens Hospital of Orange County, Orange
UC Davis Medical Center, Sacramento
Oregon Health & Science University, Portland
Shriner's Hospital for Children, Portland
Seattle Children's Hospital, Seattle
Boston Children's Hospital, Boston
Lead Sponsor
Collaborators (2)
Parexel
INDUSTRY
Dohmen Life Science Services
OTHER
PTC Therapeutics
INDUSTRY