321
Participants
Start Date
November 15, 2015
Primary Completion Date
October 30, 2020
Study Completion Date
October 30, 2020
glutamate infusion
Intravenous infusion of 0.125M L-glutamic acid solution at a rate of 1.65 ml/kg BW and hour commencing at or up to 20 minutes before the release of aortic cross-clamp. The infusion is continued for two hours after declamping the aorta after which an additional 50 ml is given at a halved infusion rate.
saline infusion
Intravenous infusion of saline at a rate of 1.65 ml/kg BW and hour commencing at or up to 20 minutes before the release of aortic cross-clamp. The infusion is continued for two hours after declamping the aorta after which an additional 50 ml is given at a halved infusion rate.
Sahlgrenska University Hospital, Gothenburg
University Hospital Linköping, Linköping
University Hospital Örebro, Örebro
University Hospital Umeå, Umeå
Region Örebro County
OTHER
University Hospital, Umeå
OTHER
Sahlgrenska University Hospital
OTHER
University Hospital, Linkoeping
OTHER