Effects of rTMS Based on Neural Activation in Language Performance in Stroke Patients With Non-fluent Aphasia

NACompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

October 20, 2023

Study Completion Date

October 20, 2023

Conditions
StrokeAphasia
Interventions
DEVICE

MagPro magnetic stimulator (HF rTMS)

Most activated area from fNIRS findings: Perilesional Broca's area. Use the true coil. High frequency rTMS (10Hz), Number of total stimuli: 800, Location: perilesional Broca's area, Intensity: 100% of resting motor threshold, Coil orientation: tangential to scalp, in combination with speech therapy(35-40min) after each rTMS session, Daily 10 treatment session

DEVICE

MagPro magnetic stimulator (sham)

Most activated area from fNIRS findings: Perilesional Broca's area. Use the sham coil. High frequency rTMS (10Hz), Number of total stimuli: 800, Location: perilesional Broca's area, Intensity: 100% of resting motor threshold, Coil orientation: tangential to scalp, in combination with speech therapy(35-40min) after each rTMS session, Daily 10 treatment session

DEVICE

MagPro magnetic stimulator (LF rTMS)

"Most activated area from fNIRS findings: Contralesional homologs of Broca's area.~Use the true coil. Low frequency rTMS (1Hz), Number of total stimuli: 1200, Location: Contralesional homologs of Broca's area (Pars triangularis), Intensity: 90% of resting motor threshold, Coil orientation: tangential to scalp, in combination with speech therapy(35-40min) after each rTMS session, Daily 10 treatment session"

Trial Locations (1)

463-707

Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam-si

All Listed Sponsors
lead

Seoul National University Bundang Hospital

OTHER

NCT02591719 - Effects of rTMS Based on Neural Activation in Language Performance in Stroke Patients With Non-fluent Aphasia | Biotech Hunter | Biotech Hunter