130
Participants
Start Date
December 31, 2015
Primary Completion Date
October 31, 2017
Study Completion Date
November 30, 2017
Magesium sulphate
\*Experimental: Group A: Magesium sulphate 4 gm intravenous (I.V) loading dose over 30 mins \& 1 gm/ hour maintenance dose for 24 hours, or till labor occurs ( whichever occurs first)
Nifedipine
\*Active Comparator: Group B Nifedipine wil be given in a loading dose of 40 mg in the 1st hour (10mg will be given every 15 min), then a maintenance dose of 60mg /24 hours, divided in 3 doses
Doppler on fetal middle cerebral artery
both group A and group B: ultrasound doppler to measure the mean pulsility index (PI) and resistance index (PI) of the middle cerebral artery in the fetus twice, once before giving them the drug, and the other after 4 hours of starting the loading dose.
11562, Cairo
Kasr El Aini Hospital
OTHER