A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction

PHASE3CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

June 30, 2017

Study Completion Date

June 2, 2017

Conditions
Fetal Growth Retardation
Interventions
DRUG

Sildenafil citrate

"In patients with Fetal Growth Restriction (FGR)and abnormal umbilical artery Doppler, will be randomly assigned and divided to 2 groups which will be treated with sildenafil citrate either placebo.~This study will compare the change in Resistance Index (RI) and the Pulsatility Index (PI) of the umbilical artery and fetal middle cerebral artery, for patients who receive 25 mg of oral sildenafil citrate 8 hourly starting at diagnosis of FGR until delivery against those who will receive placebo of the same color and shape of sildenafil citrate tablet."

DRUG

placebo

Trial Locations (1)

25187

Ain shams university maternity hospital, Cairo

All Listed Sponsors
lead

Ain Shams University

OTHER

NCT02590536 - A Trial Evaluating the Role of Sildenafil in the Treatment of Fetal Growth Restriction | Biotech Hunter | Biotech Hunter