Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes

NACompletedINTERVENTIONAL
Enrollment

110

Participants

Timeline

Start Date

October 31, 2015

Primary Completion Date

September 30, 2022

Study Completion Date

September 30, 2022

Conditions
Rotator Cuff Tear Arthropathy
Interventions
DRUG

Ibuprofen

Patients will be randomized using a computer generated number to received either ibuprofen (400mg by mouth every eight hours as needed) versus placebo for post-operative pain control in addition to opiate medication (hydrocodone/acetaminophen). Study doctors or research staff will be given randomly generated treatment allocations within sealed opaque envelopes. Once the patient is screened/qualified in surgery, the envelope will be opened and the patient randomized to the allocated treatment regimen. Patients will be given a two week supply (42 pills total) of either ibuprofen or placebo on the day of surgery upon discharge from the surgery center by a research coordinator.

DRUG

Placebo

Pharmacy formulated placebo

Trial Locations (1)

94143

UCSF Orthopaedic Institute, San Francisco

All Listed Sponsors
lead

University of California, San Francisco

OTHER

NCT02588027 - Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder Functional Outcomes | Biotech Hunter | Biotech Hunter