Studying Movement Control in Parkinson's Disease Using Closed Loop Deep Brain Stimulation

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

January 8, 2016

Primary Completion Date

July 1, 2017

Study Completion Date

December 31, 2019

Conditions
Parkinson Disease
Interventions
PROCEDURE

Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)

'Classical' high-frequency Deep Brain Stimulation, which is applied irrespective of ongoing brain activity.

PROCEDURE

closed-loop Deep Brain Stimulation applied through custom built external stimulator (Little et al., 2013, 2015)

Deep Brain Stimulation, which is applied depending on ongoing brain activity.

PROCEDURE

Deep Brain Stimulation off

Deep Brain Stimulation is turned off.

DEVICE

local field potentials and electroencephalography recordings

Simultaneous recordings of local field potentials from subthalamic nucleus and electroencephalography

Trial Locations (2)

WC1N 3BG

University College London Hospitals NHS Trust, London

OX3 9DU

Oxford University Hospitals NHS Trust, Oxford

All Listed Sponsors
lead

University of Oxford

OTHER

NCT02585154 - Studying Movement Control in Parkinson's Disease Using Closed Loop Deep Brain Stimulation | Biotech Hunter | Biotech Hunter