Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation

PHASE3CompletedINTERVENTIONAL
Enrollment

157

Participants

Timeline

Start Date

January 31, 2016

Primary Completion Date

January 31, 2020

Study Completion Date

January 31, 2020

Conditions
Liver FailureEnd Stage Liver DiseaseBiliary Tract Diseases
Interventions
PROCEDURE

Dual hypothermic oxygenated perfusion

Dual hypothermic oxygenated perfusion using the Liver Assist

DEVICE

Liver Assist®

The Liver Assist® is the device used to give the intervention dual hypothermic perfusion.

PROCEDURE

Perfusion fluid

The perfusion fluid is Belzer machine perfusion solution University of Wisconsin (Bridge-to-Life, Ltd., Northbrook, IL).

DRUG

Glutathione

Glutathione in a dosage of 3 mmol/ is added to the perfusion fluid according to the intention of use of the perfusion fluid.

Trial Locations (6)

3000

University Hospitals Leuven, Leuven

9000

Ghent University Hospital, Ghent

2333 ZA

Leiden Universtiy Medical Center, Leiden

9700 RB

University Medical Center Groningen, Groningen

3015 CE

Erasmus Medical Center, Rotterdam

Unknown

King's College Hospital NHS Trust, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Erasmus Medical Center

OTHER

collaborator

Leiden University Medical Center

OTHER

collaborator

Universitaire Ziekenhuizen KU Leuven

OTHER

collaborator

University Hospital, Ghent

OTHER

collaborator

King's College Hospital NHS Trust

OTHER

lead

Robert J. Porte

OTHER