A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 1, 2015

Primary Completion Date

December 31, 2020

Study Completion Date

March 31, 2021

Conditions
Malignant Pleural Effusion
Interventions
OTHER

Doxycycline

500 mg of doxycycline will be dissolved in 50 ml of normal saline. The combination will then be instilled through the chest tube in the pleural cavity and the chest tube drain will be clamped for 4 hours.

OTHER

Iodopovidine

20 ml of 10% betadine (Microshield, Johnson and Johnson, Solan, India) will be dissolved in 80 mL of normal saline. The combination will then be instilled through the chest tube in the pleural cavity and the chest tube drain will be clamped for 4 hours.

Trial Locations (1)

160012

Bronchoscopy suite, PGIMER, Chandigarh

All Listed Sponsors
lead

Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER

NCT02583282 - A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion | Biotech Hunter | Biotech Hunter